Immunoinformatics and tick vaccinology

نویسندگان

چکیده

Immunoinformatics is an emerging area focused on development and applications of methods used to facilitate vaccine development. There a growing interest in the field vaccinology centered new omic science named ‘vaccinomics’. However, this approach has not succeeded provide solution against major infections affecting both animals humans, since tick vaccines are still being developed based conventional biochemical or immunological dissect molecular structure pathogen, looking for candidate antigen. The availability complete genomes novel advanced technologies, such as data mining, bioinformatics, microarrays, proteomics, have revolutionized provided impulse research. aim review explore how modern will contribute discovery antigens understand research process improve existing vaccines. Under concept, age ticks make it possible design starting from prediction silico analysis gene sequences obtained by mining using computer algorithms, without need keep pathogen vitro. This genome-based been “reverse 3.0” “vaccinomics 1.0” can be applied ticks.

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ژورنال

عنوان ژورنال: Exploration of immunology

سال: 2023

ISSN: ['2768-6655']

DOI: https://doi.org/10.37349/ei.2023.00085